Medical Conditions Terminology in Category I

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Infant Diaper

Care of infants in the home or institution.

Ichthyosis

Any of several generalized skin disorders characterized by dryness, roughness, and scaliness, due to hypertrophy of the stratum corneum epidermis. Most are genetic, but some are acquired, developing in association with other systemic disease or genetic syndrome.

Intraocular Lens

Artificial implanted lenses.

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Impaired Parents Offspring

A child of one or more parents afflicted by an organic, psychiatric, or behavioral disorder. Articles on this subject tend to focus on the child from the social, behavioral, or psychological viewpoint, rather than the genetic.

IGF-Binding Protein 2

One of the six homologous soluble proteins that bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions at the cellular level.

IGF Type 1 beta Subunit Receptor

A protein-tyrosine kinase receptor that is closely related in structure to the INSULIN RECEPTOR. Although commonly referred to as the IGF-I receptor, it binds both IGF-I and IGF-II with high affinity. It is comprised of a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precusor protein. The beta subunit contains an intrisic tyrosine kinase domain. EC 2.7.11.-.

IGF Type 1 alpha Subunit Receptor

A protein-tyrosine kinase receptor that is closely related in structure to the INSULIN RECEPTOR. Although commonly referred to as the IGF-I receptor, it binds both IGF-I and IGF-II with high affinity. It is comprised of a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precusor protein. The beta subunit contains an intrisic tyrosine kinase domain. EC 2.7.11.-.

In Hospital Mortality

A vital statistic measuring or recording the rate of death from any cause in hospitalized populations.

Impulsive, Janz Petit Mal

A disorder characterized by the onset of myoclonus in adolescence, a marked increase in the incidence of absence seizures (see EPILEPSY, ABSENCE), and generalized major motor seizures (see EPILEPSY, TONIC-CLONIC). The myoclonic episodes tend to occur shortly after awakening. Seizures tend to be aggravated by sleep deprivation and alcohol consumption. Hereditary and sporadic forms have been identified. (From Adams et al., Principles of Neurology, 6th ed, p323)

Impedance, Transthoracic Plethysmography

A type of impedance plethysmography in which bioelectrical impedance is measured between electrodes positioned around the neck and around the lower thorax. It is used principally to calculate stroke volume and cardiac volume, but it is also related to myocardial contractility, thoracic fluid content, and circulation to the extremities.